WEKO3
-
RootNode
アイテム
歯胚の発育におけるVEGFとその受容体の発現
https://ohu-lib.repo.nii.ac.jp/records/2667
https://ohu-lib.repo.nii.ac.jp/records/26671da56732-fb11-4647-b381-bf8823c5f4d5
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
KJ00005073359.pdf (9.1 MB)
|
|
| Item type | 紀要論文(ELS)_JAIRO Cloud（WEKO3）対応_596d4a9f(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2007-09-01 | |||||
| タイトル | ||||||
| タイトル | 歯胚の発育におけるVEGFとその受容体の発現 | |||||
| タイトル | ||||||
| タイトル | Immunohistochemical Localization of VEGF and VEGF Receptors in Developing Human Tooth Germ | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | VEGF | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | KDR/Flk-1 | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Flt-1 | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | tooth germ | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | human | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| ページ属性 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | P(論文) | |||||
| 記事種別(日) | ||||||
| 値 | 原著論文 | |||||
| 記事種別(英) | ||||||
| 言語 | en | |||||
| 値 | Original Article | |||||
| 著者名(日) |
月田, 秀夫
× 月田, 秀夫× 安部, 仁晴× 中川, 敏浩 |
|||||
| 著者名よみ |
ツクダ, ヒデオ
× ツクダ, ヒデオ× アベ, キミハル× ナカガワ, トシヒロ |
|||||
| 著者名(英) |
TSUKIDA, Hideo
× TSUKIDA, Hideo× AMBE, Kimiharu× NAKAGAWAC, Toshihiro |
|||||
| 著者所属(日) | ||||||
| 値 | 奥羽大学歯学部生体構造学講座口腔組織学分野 | |||||
| 著者所属(日) | ||||||
| 値 | 奥羽大学歯学部生体構造学講座口腔組織学分野 | |||||
| 著者所属(日) | ||||||
| 値 | 奥羽大学歯学部生体構造学講座口腔組織学分野 | |||||
| 著者所属(英) | ||||||
| 言語 | en | |||||
| 値 | Division of Oral Histology, Department of Morphological Biology, Ohu University School of Dentistry | |||||
| 著者所属(英) | ||||||
| 言語 | en | |||||
| 値 | Division of Oral Histology, Department of Morphological Biology, Ohu University School of Dentistry | |||||
| 著者所属(英) | ||||||
| 言語 | en | |||||
| 値 | Division of Oral Histology, Department of Morphological Biology, Ohu University School of Dentistry | |||||
| 抄録(英) | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Vascular endothelial growth factor (VEGF) is a major angiogenetic factor in both developmental and wound healing processes. Recent studies have shown the expression of VEGF mRNA in lung, kidney, heart, ovary and various organs. In order to clarify the role of VEGF in developing human tooth germ, the expression of VEGF and VEGF receptors (KDR/Flk-1 and Flt-1) were investigated on the mandibular deciduous central incisors by immunohistochemistry. At fetal 12 weeks, immunoreactivity of VEGF was detected on many cells in the enamel organ, dental papilla and dental follicle. Immunoreactivity of VEGF in the dental papilla at fetal 14 weeks was localized at undifferentiated cells in adjacent inner enamel epithelium. As compared with immunoreactivity of VEGF at inner enamel epithelium, that of preameloblasts was weak at fetal 18 weeks. At fetal 21 weeks, ameloblasts and odontoblasts were positive for and VEGF. Immunoreactivity of KDR/Flk-1 was similar to that of VEGF. However, it was not visible at ameloblasts and odontoblasts. Immunoreactivity of Flt-1 was not detected in tooth germ except endothelial cells penetrating dental papilla and dental follicle. It was localized on stratum intermedium and outer enamel epithelium at fetal 21 weeks. These results suggest that VEGF, KDR/Flk-1 and Flt-1 are involved in the angiogenesis on developing tooth germ. In addition, VEGF, KDR/Flk-1 and Flt-1 may have an important role in the proliferation and differentiaton of ameloblasts and odontoblasts in human tooth germ morphogenesis. | |||||
| 雑誌書誌ID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AN1010214X | |||||
| 書誌情報 |
奥羽大学歯学誌 巻 34, 号 3, p. 75-91, 発行日 2007-09 |
|||||
