@article{oai:ohu-lib.repo.nii.ac.jp:00002235,
 author = {浜田, 節男 and 五十嵐, 栄 and 長岡, 正博 and 宮澤, 忠蔵 and 堀内, 登 and ハマダ, セツオ and イガラシ, サカエ and ナガオカ, マサヒロ and ミヤザワ, チュウゾウ and ホリウチ, ノボル and HAMADA, Setsuo and IGARASI, Sakae and NAGAOKA, Masahiro and MIYAZAWA, Chuzo and HORIUCHI, Noboru},
 issue = {1},
 journal = {奥羽大学歯学誌},
 month = {Mar},
 note = {P(論文), Since mice or rats which have had ovary extraction have bone changes similar to those of the mice, rats or women lacking in estrogen, they have been used as an animal control group to examine the reduction of bone density after menopause. Taking it into consideration that trehalose inhibits calcium from separating from bones, the authors did a 4-week oral administration of trehalose to the mice which had ovary extraction (OVX), and examined the influence of trehalose on the womb, serum components and bones. There was no significant statistical difference between the OVX and TH (trehalose) administration groups in the womb weight, the concentration of calcium and inorganic phosphorus in the serum, and the length of the femur. The weight of the femur of the TH group, to which 10 and 50mg/kg of trehalose was given, increased significantly, compared with that of the OVX group. The cortical bone and trabecula of the femur of the trehalose group became thicker and denser than those of the OVX group. These findings suggest that trehalose may be effective in the prevention of osteoporosis after menopause.},
 pages = {41--47},
 title = {卵巣摘出マウスに対するトレハロースの影響},
 volume = {31},
 year = {2004}
}