@article{oai:ohu-lib.repo.nii.ac.jp:00002237, author = {伊東, 博司 and 櫻井, 裕子 and 杉浦, 淳子 and 奥山, 典子 and 横手, 優介 and 山崎, 章 and イトウ, ヒロシ and サクライ, ユウコ and スギウラ, ジュンコ and オクヤマ, ノリコ and ヨコテ, ユウスケ and ヤマサキ, アキラ and ITO, Hiroshi and SAKURAI, Yuuko and SUGIURA, Junko and OKUYAMA, Noriko and YOKOTE, Yuhsuke and YAMASAKI, Akira}, issue = {1}, journal = {奥羽大学歯学誌}, month = {Mar}, note = {P(論文), Cyclooxygenase-2(cox-2), which synthesizes precursors of prostaglandins, is principally concerned with prostaglandin synthesis in inflammatory tissue. We evaluated the effects of a selective inhibitor of cox-2 on the number of osteoclasts in rat periodontium in non-innflammatory status. In periodontium of rats which received a selective cox-2 inhibitor for 22 weeks, the number of TRAP positive cells decreased significantly (P<0.01) compared with the cell number in periodontium of rats without the inhibitor. This result suggests that cox-2 may participate in osteoclastgenesis in periodontium of non-inflammatory status.}, pages = {49--52}, title = {シクロオキシゲナーゼ-2選択的阻害剤投与によるラット歯根膜内破骨細胞数の変動}, volume = {31}, year = {2004} }