{"created":"2023-05-15T14:18:47.593191+00:00","id":2274,"links":{},"metadata":{"_buckets":{"deposit":"b621b99b-b172-4476-9ff7-7d722b019c2e"},"_deposit":{"created_by":3,"id":"2274","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"2274"},"status":"published"},"_oai":{"id":"oai:ohu-lib.repo.nii.ac.jp:00002274","sets":["90:96:98"]},"author_link":["8500","8499","8501"],"item_1_biblio_info_14":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2004-06-30","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"112","bibliographicPageStart":"103","bibliographicVolumeNumber":"31","bibliographic_titles":[{"bibliographic_title":"奥羽大学歯学誌"}]}]},"item_1_creator_6":{"attribute_name":"著者名(日)","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"北村, 和典"}],"nameIdentifiers":[{"nameIdentifier":"8499","nameIdentifierScheme":"WEKO"}]}]},"item_1_creator_7":{"attribute_name":"著者名よみ","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"キタムラ, カズノリ"}],"nameIdentifiers":[{"nameIdentifier":"8500","nameIdentifierScheme":"WEKO"}]}]},"item_1_creator_8":{"attribute_name":"著者名(英)","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"KITAMURA, Kazunori","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"8501","nameIdentifierScheme":"WEKO"}]}]},"item_1_description_1":{"attribute_name":"ページ属性","attribute_value_mlt":[{"subitem_description":"P(論文)","subitem_description_type":"Other"}]},"item_1_description_12":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_description":"The effects of cell components (Ca-m) obtained from Candida albicans on immune response of murine were investigated. Intraperitoneal injection of Ca-m caused a significant increase in direct plaque-forming cell (PFC) numbers in the spleen, and a suppressive effect on delayed hypersensitivity in the footpad 3 days or 5 days after antigenic stimulation with sheep erythrocytes (SRBC), respectively. Injection of Ca-m and SRBC together into congenitally athymic nude mice did not elicit a greater anti-SRBC PFC response than controls without Ca-m. The mice injected with Ca-m at the time of priming SRBC and then immunized with trinitrophenylated SRBC showed a greater anti-trinitrophenyl PFC response than controls without the injection of Ca-m. In vitro proliferative response of T lymphocytes in the peritoneal exudate of C3H/HeN mice immunized with Ca-m and SRBC [T(Ca-m+SRBC)] wsa examined by determining the uptake of tritiated thymidine in to cells. Although the cells from mice which injected with SRBC only [T(SRBC)] showed a basal proliferative response in the absence of antigen, the addition of specific antigen increased the response sharply. However, the basal response of T(Ca-m+SRBC) disappeared. The basal proliferation was seen to be due to or dependent on the proliferation of Ia^+ T cells. The quantity of IL-4, but not IL-2, in the supernatant obtained from cultures containing T(Ca-m+SRBC) and anti-CD3 antibodies was higher than that of T(SRBC) and anti-CD3 antibodies cultures. These results suggest that Ca-m have an adjuvant effect on the humoral antibody response and a suppressive effect on delayed sensitivity reaction on murine immuno system, and these effects are mainly due to the enhanced induction of Th2 cells.","subitem_description_type":"Other"}]},"item_1_source_id_13":{"attribute_name":"雑誌書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AN1010214X","subitem_source_identifier_type":"NCID"}]},"item_1_text_10":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Ohu University School of Dentistry, Department of Oral Medical Science"}]},"item_1_text_2":{"attribute_name":"記事種別(日)","attribute_value_mlt":[{"subitem_text_value":"原著論文"}]},"item_1_text_3":{"attribute_name":"記事種別(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Original Article"}]},"item_1_text_9":{"attribute_name":"著者所属(日)","attribute_value_mlt":[{"subitem_text_value":"奥羽大学歯学部口腔病態解析制御学講座"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2004-06-30"}],"displaytype":"detail","filename":"KJ00004260479.pdf","filesize":[{"value":"853.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"url":"https://ohu-lib.repo.nii.ac.jp/record/2274/files/KJ00004260479.pdf"},"version_id":"b1828948-20a3-4195-9bb3-06b2161b33da"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Candida albicans","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"suppressive effects","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Th2","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"口腔内カンジダ症の免疫学的研究 : Candida albicans菌体成分の免疫応答への作用","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"口腔内カンジダ症の免疫学的研究 : Candida albicans菌体成分の免疫応答への作用"},{"subitem_title":"Effect of Cell Components from Candida albicans on Immune Response","subitem_title_language":"en"}]},"item_type_id":"1","owner":"3","path":["98"],"pubdate":{"attribute_name":"公開日","attribute_value":"2004-06-30"},"publish_date":"2004-06-30","publish_status":"0","recid":"2274","relation_version_is_last":true,"title":["口腔内カンジダ症の免疫学的研究 : Candida albicans菌体成分の免疫応答への作用"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-05-15T14:53:54.428940+00:00"}